1) Computational fluid dynamics (CFD) modeling of turbulent particle-laden flow (i.e. gas-particle and liquid-particle flows) that are widely employed in the petroleum and pharmaceutical industries. For example, fluid catalytic cracking (FCC)reactor, coal gasification, pharmaceutical batch crystallizer, powder mixer, and fluidized bed granulator. The two-phase flow CFD model is crucial in the design, scale-up, and optimization of these processes.
2) Experimental investigation of the particle-laden flow phenomena using advanced optical technique such as Particle Image Velocimetry (PIV)and Laser Doppler Velocimetry (LDV). Using these techniques, multiple flow variables are measured simultaneouly to validate the CFD model predictions and also to gain an improved understanding on the intricate particle-laden flow phenomena
3) Engineered aerosol carrier particles to deliver nanoparticulate drugs by inhalation. A novel formulation technique by means of spray-drying is develop to manufacture micron-scale carrier particles of nanoparticulate drug for inhaled drug delivery using a dry powder inhaler (DPI)