Symbiotic interfacing of proteins, namely enzymes, and materials. Specifically, we are interested in developing novel functional materials and approaches to material synthesis that exploit the exquisite properties (specificity, catalytic activity, self-assembly) and natural diversity of proteins. Within the context of this focus, we are studying how the microenvironment of proteins at material interfaces impacts protein function. An understanding of the link between protein structure, activity, and molecular environment is a requisite for designing rational strategies for incorporating proteins into materials and, more broadly, using proteins in new ways. The work in our group has considerable implications towards the use of enzymes for green chemistries, which reduce pollution and energy costs and increase safety, the design of tissue scaffolds with improved regenerative properties, the creation of biopolymers that sense and destroy toxic agents, and the development of renewable energy technologies.
