We are looking for an outstanding postdoc/Ph.D. student with an interdisciplinary background in materials science, biophysics, biomedical engineering, or chemical engineering, who will explore the role of extracellular biophysical cues (spatial distribution of ligands, elasticity, nanotopography) on the signaling and immune response of T cells.
Examples of our recent studies can be found here:
Toledo et al, Science Adv. 2021; 7 : eabc1640
Bhingardive et al, Nano Lett, 2021, 21, 10, 4241–4248
Le Saux et al, Adv. Matt 2019, 31,1805954
We have several available research projects.
In one project, a student/ postdoc will lead the design of nanostructured surfaces for addressing basic questions in the biophysics of T cells, and the relevant biological experiments, including ex-vivo T cell activation assays.
In another project, a student/ postdoc will lead the design of nanostructured surfaces for the activation and proliferation of T cells for adoptive immunotherapy against cancer.
Candidates with an interdisciplinary background that include nanoengineering, microfabrication, and biochemistry, are particularly encouraged to apply. The ability to work in an interdisciplinary research team that includes materials engineers and chemists is mandatory. Understanding T cell biology and proficiency in experimental cell biology, biomaterials, and high-resolution microscopy are advantageous. High motivation and self-learning capability are mandatory.
The applications can be sent directly to marksc@bgu.ac.il
Visit our website: www.schvartzmanlab.com