Job ID: 132394

Ph.D. Student/Postdoc Positions - Surface Tension Effects on Lung Mechanics

Stevens Institute of Technology

  • Oct. 26, 2019
  • Ph.D. Student/Postdoc Positions - Surface Tension Effects on Lung Mechanics
  • Biomedical Engineering
  • Stevens Institute of Technology
    Hoboken, NJ
  • Open until filled
  • Later
  • Graduate Student
  • Engineering Physics
    Bioengineering (all Bio-related fields)

THE OPENINGS: Two NIH-funded BME Ph.D. student/postdoctoral fellow positions in pulmonary mechanics.

THE PROBLEM: In the acute respiratory distress syndrome (ARDS), edema reduces pulmonary gas exchange. Mechanical ventilation assists gas exchange but causes ventilation induced lung injury (VILI) and impedes recovery.

OUR APPROACH AND FINDINGS: A unique method of determining surface tension in edematous alveoli of isolated rat lungs led us to (i) find that VILI is attributable to heterogeneous lung mechanics, and proportional to surface tension, and (ii) discover that a fluorescent dye has the ability to lower surface tension and reduce VILI.

PROJECT #1: Investigate biophysical mechanism through which dye lowers surface tension and reduces VILI.

PROJECT #2: Investigate mechanical mechanism of spatial propagation of VILI throughout lungs.

QUALIFICATIONS: Ph.D. student applicants must hold an undergraduate degree in biomedical engineering or a closely related engineering discipline. A master’s degree; background in cardiopulmonary mechanics or physiology; and research experience are desirable but not required. Postdoctoral fellow applicants should have training in physiology, preferably including pulmonary physiology, and mechanics.

THE PI: Dr. Carrie E. Perlman trained in mechanical engineering at MIT and biomedical engineering at Northwestern University. She was a postdoctoral fellow in pulmonary physiology at Columbia University.

THE ENVIRONMENT: Stevens, in Hoboken, NJ, provides a multidisciplinary research training environment. The beautiful campus is located on the Hudson River, directly opposite and 10 minutes by train from lower Manhattan.

CONTACT INFORMATION: Interested candidates should email Dr. Perlman at, and attach a CV.

  • Stevens Institute of Technology is an equal opportunity employer.

Please reference in your cover letter when
applying for or inquiring about this job announcement.

Contact Information

  • Carrie E. Perlman
    Biomedical Engineering
    Stevens Institute of Technology
    Castle Point On Hudson
    Hoboken, NJ 07030

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